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Exosome-Related Multi-Pass Transmembrane Protein TSAP6 Is a Target of Rhomboid Protease RHBDD1-Induced Proteolysis

We have previously reported that rhomboid domain containing 1 (RHBDD1), a mammalian rhomboid protease highly expressed in the testis, can cleave the Bcl-2 protein Bik. In this study, we identified a multi-pass transmembrane protein, tumor suppressor activated pathway-6 (TSAP6) as a potential substra...

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Detalles Bibliográficos
Autores principales: Wan, Chunhua, Fu, Jun, Wang, Yong, Miao, Shiying, Song, Wei, Wang, Linfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356283/
https://www.ncbi.nlm.nih.gov/pubmed/22624035
http://dx.doi.org/10.1371/journal.pone.0037452