Probing Molecular Mechanisms of the Hsp90 Chaperone: Biophysical Modeling Identifies Key Regulators of Functional Dynamics

Deciphering functional mechanisms of the Hsp90 chaperone machinery is an important objective in cancer biology aiming to facilitate discovery of targeted anti-cancer therapies. Despite significant advances in understanding structure and function of molecular chaperones, organizing molecular principl...

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Detalles Bibliográficos
Autores principales: Dixit, Anshuman, Verkhivker, Gennady M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356286/
https://www.ncbi.nlm.nih.gov/pubmed/22624053
http://dx.doi.org/10.1371/journal.pone.0037605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356286/
https://www.ncbi.nlm.nih.gov/pubmed/22624053
http://dx.doi.org/10.1371/journal.pone.0037605

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