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Probing Molecular Mechanisms of the Hsp90 Chaperone: Biophysical Modeling Identifies Key Regulators of Functional Dynamics

Deciphering functional mechanisms of the Hsp90 chaperone machinery is an important objective in cancer biology aiming to facilitate discovery of targeted anti-cancer therapies. Despite significant advances in understanding structure and function of molecular chaperones, organizing molecular principl...

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Detalles Bibliográficos
Autores principales:	Dixit, Anshuman, Verkhivker, Gennady M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356286/ https://www.ncbi.nlm.nih.gov/pubmed/22624053 http://dx.doi.org/10.1371/journal.pone.0037605

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