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Genetic Variation in the β2-Adrenocepter Gene Is Associated with Susceptibility to Bacterial Meningitis in Adults

Recently, the biased β2-adrenoceptor/β-arrestin pathway was shown to play a pivotal role in crossing of the blood brain barrier by Neisseria meningitidis. We hypothesized that genetic variation in the β2-adrenoceptor gene (ADRB2) may influence susceptibility to bacterial meningitis. In a prospective...

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Detalles Bibliográficos
Autores principales: Adriani, Kirsten S., Brouwer, Matthijs C., Baas, Frank, Zwinderman, Aeilko H., van der Ende, Arie, van de Beek, Diederik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356289/
https://www.ncbi.nlm.nih.gov/pubmed/22624056
http://dx.doi.org/10.1371/journal.pone.0037618