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Genetic Variation in the β2-Adrenocepter Gene Is Associated with Susceptibility to Bacterial Meningitis in Adults
Recently, the biased β2-adrenoceptor/β-arrestin pathway was shown to play a pivotal role in crossing of the blood brain barrier by Neisseria meningitidis. We hypothesized that genetic variation in the β2-adrenoceptor gene (ADRB2) may influence susceptibility to bacterial meningitis. In a prospective...
Autores principales: | Adriani, Kirsten S., Brouwer, Matthijs C., Baas, Frank, Zwinderman, Aeilko H., van der Ende, Arie, van de Beek, Diederik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356289/ https://www.ncbi.nlm.nih.gov/pubmed/22624056 http://dx.doi.org/10.1371/journal.pone.0037618 |
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