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Analysis of C3 Suggests Three Periods of Positive Selection Events and Different Evolutionary Patterns between Fish and Mammals

BACKGROUND: The third complement component (C3) is a central protein of the complement system conserved from fish to mammals. It also showed distinct characteristics in different animal groups. Striking features of the fish complement system were unveiled, including prominent levels of extrahepatic...

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Detalles Bibliográficos
Autores principales: Meng, Fanxing, Sun, Yuena, Liu, Xuezhu, Wang, Jianxin, Xu, Tianjun, Wang, Rixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356312/
https://www.ncbi.nlm.nih.gov/pubmed/22624039
http://dx.doi.org/10.1371/journal.pone.0037489