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Macrophages Help NK Cells to Attack Tumor Cells by Stimulatory NKG2D Ligand but Protect Themselves from NK Killing by Inhibitory Ligand Qa-1

Natural killer (NK) cells and their crosstalk with other immune cells are important for innate immunity against tumor. To explore the role of the interaction between NK cells and macrophages in the regulation of anti-tumor activities of NK cells, we here demonstrate that poly I:C-treated macrophages...

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Detalles Bibliográficos
Autores principales: Zhou, Zhixia, Zhang, Cai, Zhang, Jian, Tian, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356357/
https://www.ncbi.nlm.nih.gov/pubmed/22629344
http://dx.doi.org/10.1371/journal.pone.0036928