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REDD1 Protects Osteoblast Cells from Gamma Radiation-Induced Premature Senescence

Radiotherapy is commonly used for cancer treatment. However, it often results in side effects due to radiation damage in normal tissue, such as bone marrow (BM) failure. Adult hematopoietic stem and progenitor cells (HSPC) reside in BM next to the endosteal bone surface, which is lined primarily by...

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Detalles Bibliográficos
Autores principales: Li, Xiang Hong, Ha, Cam T., Fu, Dadin, Xiao, Mang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356368/
https://www.ncbi.nlm.nih.gov/pubmed/22629318
http://dx.doi.org/10.1371/journal.pone.0036604