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Bacillus licheniformis BlaR1 L3 Loop Is a Zinc Metalloprotease Activated by Self-Proteolysis

In Bacillus licheniformis 749/I, BlaP β-lactamase is induced by the presence of a β-lactam antibiotic outside the cell. The first step in the induction mechanism is the detection of the antibiotic by the membrane-bound penicillin receptor BlaR1 that is composed of two functional domains: a carboxy-t...

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Detalles Bibliográficos
Autores principales: Berzigotti, Stéphanie, Benlafya, Kamal, Sépulchre, Jérémy, Amoroso, Ana, Joris, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356374/
https://www.ncbi.nlm.nih.gov/pubmed/22623956
http://dx.doi.org/10.1371/journal.pone.0036400