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EGFR Soluble Isoforms and Their Transcripts Are Expressed in Meningiomas

The EGFR (epidermal growth factor receptor) is involved in the oncogenesis of many tumors. In addition to the full-length EGFR (isoform a), normal and tumor cells produce soluble EGFR isoforms (sEGFR) that lack the intracellular domain. sEGFR isoforms b, c and d are encoded by EGFR variants 2 (v2),...

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Detalles Bibliográficos
Autores principales: Guillaudeau, Angélique, Durand, Karine, Bessette, Barbara, Chaunavel, Alain, Pommepuy, Isabelle, Projetti, Fabrice, Robert, Sandrine, Caire, François, Rabinovitch-Chable, Hélène, Labrousse, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356382/
https://www.ncbi.nlm.nih.gov/pubmed/22623992
http://dx.doi.org/10.1371/journal.pone.0037204