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Topological Domains in Mammalian Genomes Identified by Analysis of Chromatin Interactions

The spatial organization of the genome is intimately linked to its biological function, yet our understanding of higher order genomic structure is coarse, fragmented and incomplete. In the nucleus of eukaryotic cells, interphase chromosomes occupy distinct chromosome territories (CT), and numerous m...

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Detalles Bibliográficos
Autores principales: Dixon, Jesse R., Selvaraj, Siddarth, Yue, Feng, Kim, Audrey, Li, Yan, Shen, Yin, Hu, Ming, Liu, Jun S., Ren, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356448/
https://www.ncbi.nlm.nih.gov/pubmed/22495300
http://dx.doi.org/10.1038/nature11082