Structure of the human kappa opioid receptor in complex with JDTic

Opioid receptors (ORs) mediate the actions of endogenous and exogenous opioids for many essential physiological processes including regulation of pain, respiratory drive, mood, and, in the case of κ-opioid receptors (KOR), dysphoria and psychotomimesis. Here we report the crystal structure of the hu...

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Detalles Bibliográficos
Autores principales: Wu, Huixian, Wacker, Daniel, Katritch, Vsevolod, Mileni, Mauro, Han, Gye Won, Vardy, Eyal, Liu, Wei, Thompson, Aaron A., Huang, Xi-Ping, Carroll, F. Ivy, Mascarella, S. Wayne, Westkaemper, Richard B., Mosier, Philip D., Roth, Bryan L., Cherezov, Vadim, Stevens, Raymond C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356457/
https://www.ncbi.nlm.nih.gov/pubmed/22437504
http://dx.doi.org/10.1038/nature10939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356457/
https://www.ncbi.nlm.nih.gov/pubmed/22437504
http://dx.doi.org/10.1038/nature10939

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