Pharmacokinetic study of neural stem cell-based cell carrier for oncolytic virotherapy: Targeted delivery of the therapeutic payload in an orthotopic brain tumor model

Oncolytic virotherapy is a promising novel therapy for glioblastoma that needs to be optimized before introduced to clinic. The targeting of conditionally replicating adenoviruses (CRAds) can be improved by relying on the tumor tropic properties of neural stem cells (NSCs). Here, we report the chara...

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Detalles Bibliográficos
Autores principales: Thaci, Bart, Ahmed, Atique U., Ulasov, Ilya V., Tobias, Alex L., Han, Yu, Aboody, Karen S., Lesniak, Maciej S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356460/
https://www.ncbi.nlm.nih.gov/pubmed/22555507
http://dx.doi.org/10.1038/cgt.2012.21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356460/
https://www.ncbi.nlm.nih.gov/pubmed/22555507
http://dx.doi.org/10.1038/cgt.2012.21

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