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Implication of Crystal Water Molecules in Inhibitor Binding at ALR2 Active Site

Water molecules play a crucial role in mediating the interaction between a ligand and a macromolecule. The solvent environment around such biomolecule controls their structure and plays important role in protein-ligand interactions. An understanding of the nature and role of these water molecules in...

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Detalles Bibliográficos
Autores principales: Hymavati, Kumar, Vivek, Elizabeth Sobhia, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356870/
https://www.ncbi.nlm.nih.gov/pubmed/22649481
http://dx.doi.org/10.1155/2012/541594