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Implication of Crystal Water Molecules in Inhibitor Binding at ALR2 Active Site
Water molecules play a crucial role in mediating the interaction between a ligand and a macromolecule. The solvent environment around such biomolecule controls their structure and plays important role in protein-ligand interactions. An understanding of the nature and role of these water molecules in...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356870/ https://www.ncbi.nlm.nih.gov/pubmed/22649481 http://dx.doi.org/10.1155/2012/541594 |