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Effect of rolipram, a phosphodiesterase enzyme type–4 inhibitor, on γ-amino butyric acid content of the frontal cortex in mice exposed to chronic mild stress
OBJECTIVES: To investigate the alterations in GABA levels by rolipram in the model of depression. MATERIALS AND METHODS: The alteration of GABA content by rolipram as a phosphodiesterase enzyme type-4 inhibitor in the frontal cortex (FCx; as a brain region crucial for the control of emotion and cogn...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356953/ https://www.ncbi.nlm.nih.gov/pubmed/22629087 http://dx.doi.org/10.4103/0976-500X.95509 |