Chemical Inhibition of Bacterial Protein Tyrosine Phosphatase Suppresses Capsule Production

Capsule polysaccharide is a major virulence factor for a wide range of bacterial pathogens, including Streptococcus pneumoniae. The biosynthesis of Wzy-dependent capsules in both Gram-negative and –positive bacteria is regulated by a system involving a protein tyrosine phosphatase (PTP) and a protei...

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Detalles Bibliográficos
Autores principales: Standish, Alistair J., Salim, Angela A., Zhang, Hua, Capon, Robert J., Morona, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356977/
https://www.ncbi.nlm.nih.gov/pubmed/22629313
http://dx.doi.org/10.1371/journal.pone.0036312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356977/
https://www.ncbi.nlm.nih.gov/pubmed/22629313
http://dx.doi.org/10.1371/journal.pone.0036312

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