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Chemical Inhibition of Bacterial Protein Tyrosine Phosphatase Suppresses Capsule Production
Capsule polysaccharide is a major virulence factor for a wide range of bacterial pathogens, including Streptococcus pneumoniae. The biosynthesis of Wzy-dependent capsules in both Gram-negative and –positive bacteria is regulated by a system involving a protein tyrosine phosphatase (PTP) and a protei...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356977/ https://www.ncbi.nlm.nih.gov/pubmed/22629313 http://dx.doi.org/10.1371/journal.pone.0036312 |