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Patterns of placental development evaluated by X chromosome inactivation profiling provide a basis to evaluate the origin of epigenetic variation

BACKGROUND: Inactivation of the maternally or paternally derived X chromosome (XCI) initially occurs in a random manner in early development; however as tissues form, a ‘patchiness’ will occur in terms of which X is inactivated if cells positioned near each other are clonally descended from a common...

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Detalles Bibliográficos
Autores principales: Peñaherrera, M.S., Jiang, R., Avila, L., Yuen, R.K.C., Brown, C.J., Robinson, W.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357192/
https://www.ncbi.nlm.nih.gov/pubmed/22431562
http://dx.doi.org/10.1093/humrep/des072