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The Novel Therapeutic Effect of Phosphoinositide 3-Kinase-γ Inhibitor AS605240 in Autoimmune Diabetes

Type 1 diabetes (T1D) remains a major health problem worldwide, with a steadily rising incidence yet no cure. Phosphoinositide 3-kinase-γ (PI3Kγ), a member of a family of lipid kinases expressed primarily in leukocytes, has been the subject of substantial research for its role in inflammatory diseas...

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Detalles Bibliográficos
Autores principales: Azzi, Jamil, Moore, Robert F., Elyaman, Wassim, Mounayar, Marwan, El Haddad, Najib, Yang, Sunmi, Jurewicz, Mollie, Takakura, Ayumi, Petrelli, Alessandra, Fiorina, Paolo, Ruckle, Thomas, Abdi, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357271/
https://www.ncbi.nlm.nih.gov/pubmed/22403300
http://dx.doi.org/10.2337/db11-0134