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Sex-Specific Effect of Estrogen Sulfotransferase on Mouse Models of Type 2 Diabetes

Estrogen sulfotransferase (EST), the enzyme responsible for the sulfonation and inactivation of estrogens, plays an important role in estrogen homeostasis. In this study, we showed that induction of hepatic Est is a common feature of type 2 diabetes. Loss of Est in female mice improved metabolic fun...

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Detalles Bibliográficos
Autores principales: Gao, Jie, He, Jinhan, Shi, Xiongjie, Stefanovic-Racic, Maja, Xu, Meishu, O’Doherty, Robert Martin, Garcia-Ocana, Adolfo, Xie, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357292/
https://www.ncbi.nlm.nih.gov/pubmed/22438574
http://dx.doi.org/10.2337/db11-1152