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Sex-Specific Effect of Estrogen Sulfotransferase on Mouse Models of Type 2 Diabetes
Estrogen sulfotransferase (EST), the enzyme responsible for the sulfonation and inactivation of estrogens, plays an important role in estrogen homeostasis. In this study, we showed that induction of hepatic Est is a common feature of type 2 diabetes. Loss of Est in female mice improved metabolic fun...
Autores principales: | Gao, Jie, He, Jinhan, Shi, Xiongjie, Stefanovic-Racic, Maja, Xu, Meishu, O’Doherty, Robert Martin, Garcia-Ocana, Adolfo, Xie, Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357292/ https://www.ncbi.nlm.nih.gov/pubmed/22438574 http://dx.doi.org/10.2337/db11-1152 |
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