Class II Histone Deacetylases Downregulate GLUT4 Transcription in Response to Increased cAMP Signaling in Cultured Adipocytes and Fasting Mice

Insulin-mediated glucose uptake is highly sensitive to the levels of the facilitative glucose transporter protein, GLUT4. Repression of GLUT4 expression is correlated with insulin resistance in adipose tissue. We have shown that differentiation-dependent GLUT4 transcription was under control of clas...

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Detalles Bibliográficos
Autores principales: Weems, Juston C., Griesel, Beth A., Olson, Ann Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357296/
https://www.ncbi.nlm.nih.gov/pubmed/22403301
http://dx.doi.org/10.2337/db11-0737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357296/
https://www.ncbi.nlm.nih.gov/pubmed/22403301
http://dx.doi.org/10.2337/db11-0737

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