Inhibition of Hypothalamic Inflammation Reverses Diet-Induced Insulin Resistance in the Liver

Defective liver gluconeogenesis is the main mechanism leading to fasting hyperglycemia in type 2 diabetes, and, in concert with steatosis, it is the hallmark of hepatic insulin resistance. Experimental obesity results, at least in part, from hypothalamic inflammation, which leads to leptin resistanc...

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Detalles Bibliográficos
Autores principales: Milanski, Marciane, Arruda, Ana P., Coope, Andressa, Ignacio-Souza, Letícia M., Nunez, Carla E., Roman, Erika A., Romanatto, Talita, Pascoal, Livia B., Caricilli, Andrea M., Torsoni, Marcio A., Prada, Patricia O., Saad, Mario J., Velloso, Licio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Obesity Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357298/
https://www.ncbi.nlm.nih.gov/pubmed/22522614
http://dx.doi.org/10.2337/db11-0390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357298/
https://www.ncbi.nlm.nih.gov/pubmed/22522614
http://dx.doi.org/10.2337/db11-0390

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