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The ATP-P2X(7) Signaling Axis Is Dispensable for Obesity-Associated Inflammasome Activation in Adipose Tissue

Inflammasome activation in adipose tissue has been implicated in obesity-associated insulin resistance and type 2 diabetes. However, when and how inflammasome is activated in adipose tissue remains speculative. Here we test the hypothesis that extracellular ATP, a potent stimulus of inflammasome in...

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Detalles Bibliográficos
Autores principales: Sun, Shengyi, Xia, Sheng, Ji, Yewei, Kersten, Sander, Qi, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357307/
https://www.ncbi.nlm.nih.gov/pubmed/22415881
http://dx.doi.org/10.2337/db11-1389