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The ATP-P2X(7) Signaling Axis Is Dispensable for Obesity-Associated Inflammasome Activation in Adipose Tissue
Inflammasome activation in adipose tissue has been implicated in obesity-associated insulin resistance and type 2 diabetes. However, when and how inflammasome is activated in adipose tissue remains speculative. Here we test the hypothesis that extracellular ATP, a potent stimulus of inflammasome in...
Autores principales: | Sun, Shengyi, Xia, Sheng, Ji, Yewei, Kersten, Sander, Qi, Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357307/ https://www.ncbi.nlm.nih.gov/pubmed/22415881 http://dx.doi.org/10.2337/db11-1389 |
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