Antimalarial Iron Chelator, FBS0701, Shows Asexual and Gametocyte Plasmodium falciparum Activity and Single Oral Dose Cure in a Murine Malaria Model

Iron chelators for the treatment of malaria have proven therapeutic activity in vitro and in vivo in both humans and mice, but their clinical use is limited by the unsuitable absorption and pharmacokinetic properties of the few available iron chelators. FBS0701, (S)3”-(HO)-desazadesferrithiocin-poly...

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Detalles Bibliográficos
Autores principales: Ferrer, Patricia, Tripathi, Abhai K., Clark, Martha A., Hand, Carla Cerami, Rienhoff, Hugh Young, Sullivan, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357340/
https://www.ncbi.nlm.nih.gov/pubmed/22629364
http://dx.doi.org/10.1371/journal.pone.0037171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357340/
https://www.ncbi.nlm.nih.gov/pubmed/22629364
http://dx.doi.org/10.1371/journal.pone.0037171

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