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Poly(β-Amino Ester)-Nanoparticle Mediated Transfection of Retinal Pigment Epithelial Cells In Vitro and In Vivo

A variety of genetic diseases in the retina, including retinitis pigmentosa and leber congenital amaurosis, might be excellent targets for gene delivery as treatment. A major challenge in non-viral gene delivery remains finding a safe and effective delivery system. Poly(beta-amino ester)s (PBAEs) ha...

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Detalles Bibliográficos
Autores principales: Sunshine, Joel C., Sunshine, Sarah B., Bhutto, Imran, Handa, James T., Green, Jordan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357345/
https://www.ncbi.nlm.nih.gov/pubmed/22629417
http://dx.doi.org/10.1371/journal.pone.0037543