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Induction of Selective Blood-Tumor Barrier Permeability and Macromolecular Transport by a Biostable Kinin B1 Receptor Agonist in a Glioma Rat Model

Treatment of malignant glioma with chemotherapy is limited mostly because of delivery impediment related to the blood-brain tumor barrier (BTB). B1 receptors (B1R), inducible prototypical G-protein coupled receptors (GPCR) can regulate permeability of vessels including possibly that of brain tumors....

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Detalles Bibliográficos
Autores principales: Côté, Jérôme, Bovenzi, Veronica, Savard, Martin, Dubuc, Céléna, Fortier, Audrey, Neugebauer, Witold, Tremblay, Luc, Müller-Esterl, Werner, Tsanaclis, Ana-Maria, Lepage, Martin, Fortin, David, Gobeil, Fernand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357387/
https://www.ncbi.nlm.nih.gov/pubmed/22629405
http://dx.doi.org/10.1371/journal.pone.0037485