Additive and Transcript-Specific Effects of KPAP1 and TbRND Activities on 3′ Non-Encoded Tail Characteristics and mRNA Stability in Trypanosoma brucei

Short, non-encoded oligo(A), oligo(U), or A/U tails can impact mRNA stability in kinetoplastid mitochondria. However, a comprehensive picture of the relative effects of these modifications in RNA stability is lacking. Furthermore, while the U-preferring exoribonuclease TbRND acts on U-tailed gRNAs,...

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Detalles Bibliográficos
Autores principales: Zimmer, Sara L., McEvoy, Sarah M., Menon, Sarita, Read, Laurie K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357391/
https://www.ncbi.nlm.nih.gov/pubmed/22629436
http://dx.doi.org/10.1371/journal.pone.0037639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357391/
https://www.ncbi.nlm.nih.gov/pubmed/22629436
http://dx.doi.org/10.1371/journal.pone.0037639

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