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Neural Crest Cell Survival Is Dependent on Rho Kinase and Is Required for Development of the Mid Face in Mouse Embryos

Neural crest cells (NCC) give rise to much of the tissue that forms the vertebrate head and face, including cartilage and bone, cranial ganglia and teeth. In this study we show that conditional expression of a dominant-negative (DN) form of Rho kinase (Rock) in mouse NCC results in severe hypoplasia...

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Detalles Bibliográficos
Autores principales: Phillips, Helen M., Papoutsi, Tania, Soenen, Helena, Ybot-Gonzalez, Patricia, Henderson, Deborah J., Chaudhry, Bill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357402/
https://www.ncbi.nlm.nih.gov/pubmed/22629443
http://dx.doi.org/10.1371/journal.pone.0037685