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Neural Crest Cell Survival Is Dependent on Rho Kinase and Is Required for Development of the Mid Face in Mouse Embryos
Neural crest cells (NCC) give rise to much of the tissue that forms the vertebrate head and face, including cartilage and bone, cranial ganglia and teeth. In this study we show that conditional expression of a dominant-negative (DN) form of Rho kinase (Rock) in mouse NCC results in severe hypoplasia...
Autores principales: | Phillips, Helen M., Papoutsi, Tania, Soenen, Helena, Ybot-Gonzalez, Patricia, Henderson, Deborah J., Chaudhry, Bill |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357402/ https://www.ncbi.nlm.nih.gov/pubmed/22629443 http://dx.doi.org/10.1371/journal.pone.0037685 |
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