MDA-7/IL-24 Induces Bcl-2 Denitrosylation and Ubiquitin-Degradation Involved in Cancer Cell Apoptosis

MDA-7/IL-24 was involved in the specific cancer apoptosis through suppression of Bcl-2 expression, which is a key apoptosis regulatory protein of the mitochondrial death pathway. However, the underlying mechanisms of this regulation are unclear. We report here that tumor-selective replicating adenov...

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Detalles Bibliográficos
Autores principales: Tian, Hui, Wang, Jing, Zhang, BaoFu, Di, JieHui, Chen, FeiFei, Li, HuiZhong, Li, LianTao, Pei, DongSheng, Zheng, JunNian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357419/
https://www.ncbi.nlm.nih.gov/pubmed/22629368
http://dx.doi.org/10.1371/journal.pone.0037200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357419/
https://www.ncbi.nlm.nih.gov/pubmed/22629368
http://dx.doi.org/10.1371/journal.pone.0037200

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