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High-Dose, Extended-Interval Colistin Administration in Critically Ill Patients: Is This the Right Dosing Strategy? A Preliminary Study

Background. Gram-negative bacteria susceptible only to colistin (COS) are emerging causes of severe nosocomial infections, reviving interest in the use of colistin. However, consensus on the most effective way to administer colistin has not yet been reached. Methods. All patients who had sepsis due...

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Detalles Bibliográficos
Autores principales: Dalfino, Lidia, Puntillo, Filomena, Mosca, Adriana, Monno, Rosa, Spada, Maria Luigia, Coppolecchia, Sara, Miragliotta, Giuseppe, Bruno, Francesco, Brienza, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357480/
https://www.ncbi.nlm.nih.gov/pubmed/22423120
http://dx.doi.org/10.1093/cid/cis286