Cargando…

Intracellular Loop 2 Peptides of the Human 5HT1a Receptor are Differential Activators of Gi

Peptide mimics of intracellular loop 2 (ic2) of the human 5HT1a receptor have been studied with respect to their ability to inhibit agonist binding via interference with receptor-G-protein coupling. These peptides give shallow concentration-effect relationships. Additionally, these peptides have bee...

Descripción completa

Detalles Bibliográficos
Autores principales: Hall, Brian, Squires, Carley, Parker, Keith K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357532/
https://www.ncbi.nlm.nih.gov/pubmed/22649462
http://dx.doi.org/10.1155/2012/490734