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Suppression of the Nuclear Factor Eny2 Increases Insulin Secretion in Poorly Functioning INS-1E Insulinoma Cells

Eny2, the mammalian ortholog of yeast Sus1 and drosophila E(y)2, is a nuclear factor that participates in several steps of gene transcription and in mRNA export. We had previously found that Eny2 expression changes in mouse pancreatic islets during the metabolic adaptation to pregnancy. We therefore...

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Detalles Bibliográficos
Autores principales: Dames, P., Weise, M., Puff, R., Göke, B., Parhofer, K. G., Seissler, J., Lechner, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357931/
https://www.ncbi.nlm.nih.gov/pubmed/22649445
http://dx.doi.org/10.1155/2012/460869