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Selection of a MCF-7 Breast Cancer Cell Subpopulation with High Sensitivity to IL-1β: Characterization of and Correlation between Morphological and Molecular Changes Leading to Increased Invasiveness

Cancer and inflammation are closely related in tumor malignancy prognosis. Breast cancer MCF-7 cells have a poor invasive phenotype, although, under IL-1β stimulus, acquire invasive features. Cell response heterogeneity has precluded precise evaluation of the malignant transition. MCF-7A3 cells were...

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Detalles Bibliográficos
Autores principales: Pérez-Yépez, Eloy Andres, Ayala-Sumuano, Jorge-Tonatiuh, Reveles-Espinoza, Alicia Maria, Meza, Isaura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357940/
https://www.ncbi.nlm.nih.gov/pubmed/22655200
http://dx.doi.org/10.1155/2012/609148