Preparation and evaluation of polymeric microparticulates for improving cellular uptake of gemcitabine

BACKGROUND: Gemcitabine must be administered at high doses to elicit the required therapeutic response because of its very short plasma half-life due to rapid metabolism. These high doses can have severe adverse effects. METHODS: In this study, polymeric microparticulate systems of gemcitabine were...

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Detalles Bibliográficos
Autores principales: Lim, Ji-Ho, You, Sung-Kyun, Baek, Jong-Suep, Hwang, Chan-Ju, Na, Young-Guk, Shin, Sang-Chul, Cho, Cheong-Weon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357977/
https://www.ncbi.nlm.nih.gov/pubmed/22661887
http://dx.doi.org/10.2147/IJN.S30465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357977/
https://www.ncbi.nlm.nih.gov/pubmed/22661887
http://dx.doi.org/10.2147/IJN.S30465

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