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Preparation and evaluation of polymeric microparticulates for improving cellular uptake of gemcitabine

BACKGROUND: Gemcitabine must be administered at high doses to elicit the required therapeutic response because of its very short plasma half-life due to rapid metabolism. These high doses can have severe adverse effects. METHODS: In this study, polymeric microparticulate systems of gemcitabine were...

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Detalles Bibliográficos
Autores principales:	Lim, Ji-Ho, You, Sung-Kyun, Baek, Jong-Suep, Hwang, Chan-Ju, Na, Young-Guk, Shin, Sang-Chul, Cho, Cheong-Weon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357977/ https://www.ncbi.nlm.nih.gov/pubmed/22661887 http://dx.doi.org/10.2147/IJN.S30465

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