Low glucose under hypoxic conditions induces unfolded protein response and produces reactive oxygen species in lens epithelial cells

Aging is enhanced by hypoxia and oxidative stress. As the lens is located in the hypoglycemic environment under hypoxia, aging lens with diabetes might aggravate these stresses. This study was designed to examine whether low glucose under hypoxic conditions induces the unfolded protein response (UPR...

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Detalles Bibliográficos
Autores principales: Elanchezhian, R, Palsamy, P, Madson, C J, Mulhern, M L, Lynch, D W, Troia, A M, Usukura, J, Shinohara, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358018/
https://www.ncbi.nlm.nih.gov/pubmed/22513875
http://dx.doi.org/10.1038/cddis.2012.40

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358018/
https://www.ncbi.nlm.nih.gov/pubmed/22513875
http://dx.doi.org/10.1038/cddis.2012.40

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