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Soy Isoflavones Genistein and Daidzein Exert Anti-Apoptotic Actions via a Selective ER-mediated Mechanism in Neurons following HIV-1 Tat(1–86) Exposure

BACKGROUND: HIV-1 viral protein Tat partially mediates the neural dysfunction and neuronal cell death associated with HIV-1 induced neurodegeneration and neurocognitive disorders. Soy isoflavones provide protection against various neurotoxic insults to maintain neuronal function and thus help preser...

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Detalles Bibliográficos
Autores principales: Adams, Sheila M., Aksenova, Marina V., Aksenov, Michael Y., Mactutus, Charles F., Booze, Rosemarie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358258/
https://www.ncbi.nlm.nih.gov/pubmed/22629415
http://dx.doi.org/10.1371/journal.pone.0037540