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Soy Isoflavones Genistein and Daidzein Exert Anti-Apoptotic Actions via a Selective ER-mediated Mechanism in Neurons following HIV-1 Tat(1–86) Exposure
BACKGROUND: HIV-1 viral protein Tat partially mediates the neural dysfunction and neuronal cell death associated with HIV-1 induced neurodegeneration and neurocognitive disorders. Soy isoflavones provide protection against various neurotoxic insults to maintain neuronal function and thus help preser...
Autores principales: | Adams, Sheila M., Aksenova, Marina V., Aksenov, Michael Y., Mactutus, Charles F., Booze, Rosemarie M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358258/ https://www.ncbi.nlm.nih.gov/pubmed/22629415 http://dx.doi.org/10.1371/journal.pone.0037540 |
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