Ezrin Ubiquitylation by the E3 Ubiquitin Ligase, WWP1, and Consequent Regulation of Hepatocyte Growth Factor Receptor Activity

The membrane cytoskeleton linker ezrin participates in several functions downstream of the receptor Met in response to Hepatocyte Growth Factor (HGF) stimulation. Here we report a novel interaction of ezrin with a HECT E3 ubiquitin ligase, WWP1/Aip5/Tiul1, a potential oncogene that undergoes genomic...

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Detalles Bibliográficos
Autores principales: Zaarour, Rania F., Chirivino, Dafne, Maestro, Laurence Del, Daviet, Laurent, Atfi, Azeddine, Louvard, Daniel, Arpin, Monique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358263/
https://www.ncbi.nlm.nih.gov/pubmed/22629406
http://dx.doi.org/10.1371/journal.pone.0037490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358263/
https://www.ncbi.nlm.nih.gov/pubmed/22629406
http://dx.doi.org/10.1371/journal.pone.0037490

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