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Weekly Intra-Amniotic IGF-1 Treatment Increases Growth of Growth-Restricted Ovine Fetuses and Up-Regulates Placental Amino Acid Transporters

Frequent treatment of the growth-restricted (IUGR) ovine fetus with intra-amniotic IGF-1 increases fetal growth. We aimed to determine whether increased growth was maintained with an extended dosing interval and to examine possible mechanisms. Pregnant ewes were allocated to three groups: Control, a...

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Detalles Bibliográficos
Autores principales: Wali, Jibran A., de Boo, Hendrina A., Derraik, José G. B., Phua, Hui Hui, Oliver, Mark H., Bloomfield, Frank H., Harding, Jane E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358268/
https://www.ncbi.nlm.nih.gov/pubmed/22629469
http://dx.doi.org/10.1371/journal.pone.0037899