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AAV2-Mediated Subretinal Gene Transfer of mIL-27p28 Attenuates Experimental Autoimmune Uveoretinitis in Mice

BACKGROUND: Advances in gene transfer techniques have provided long-term, safe and stable transduction of retinal cells following subretinal injection with adeno-associated viral (AAV) vectors. In this study we investigated whether subretinal injection of AAV2-murine IL-27p28 vector was effective in...

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Detalles Bibliográficos
Autores principales: Shao, Ju, Tian, Lichun, Lei, Bo, Wei, Lin, Yang, Yan, Kijlstra, Aize, Yang, Peizeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358269/
https://www.ncbi.nlm.nih.gov/pubmed/22629453
http://dx.doi.org/10.1371/journal.pone.0037773