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Junín Virus Infection Activates the Type I Interferon Pathway in a RIG-I-Dependent Manner

Junín virus (JUNV), an arenavirus, is the causative agent of Argentine hemorrhagic fever, an infectious human disease with 15–30% case fatality. The pathogenesis of AHF is still not well understood. Elevated levels of interferon and cytokines are reported in AHF patients, which might be correlated t...

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Detalles Bibliográficos
Autores principales: Huang, Cheng, Kolokoltsova, Olga A., Yun, Nadezdha E., Seregin, Alexey V., Poussard, Allison L., Walker, Aida G., Brasier, Allan R., Zhao, Yingxin, Tian, Bing, de la Torre, Juan Carlos, Paessler, Slobodan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358329/
https://www.ncbi.nlm.nih.gov/pubmed/22629479
http://dx.doi.org/10.1371/journal.pntd.0001659