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Junín Virus Infection Activates the Type I Interferon Pathway in a RIG-I-Dependent Manner
Junín virus (JUNV), an arenavirus, is the causative agent of Argentine hemorrhagic fever, an infectious human disease with 15–30% case fatality. The pathogenesis of AHF is still not well understood. Elevated levels of interferon and cytokines are reported in AHF patients, which might be correlated t...
Autores principales: | Huang, Cheng, Kolokoltsova, Olga A., Yun, Nadezdha E., Seregin, Alexey V., Poussard, Allison L., Walker, Aida G., Brasier, Allan R., Zhao, Yingxin, Tian, Bing, de la Torre, Juan Carlos, Paessler, Slobodan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358329/ https://www.ncbi.nlm.nih.gov/pubmed/22629479 http://dx.doi.org/10.1371/journal.pntd.0001659 |
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