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Dental methacrylates may exert genotoxic effects via the oxidative induction of DNA double strand breaks and the inhibition of their repair

Methacrylate monomers used in dentistry have been shown to induce DNA double strand breaks (DSBs), one of the most serious DNA damage. In the present work we show that a model dental adhesive consisting of 45% 2-hydroxyethyl methacrylate (HEMA) and 55% bisphenol A-diglycidyl dimethacrylate (Bis-GMA)...

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Detalles Bibliográficos
Autores principales: Blasiak, Janusz, Synowiec, Ewelina, Tarnawska, Justyna, Czarny, Piotr, Poplawski, Tomasz, Reiter, Russel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358545/
https://www.ncbi.nlm.nih.gov/pubmed/22327778
http://dx.doi.org/10.1007/s11033-012-1582-3