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Expression of TopBP1 in hereditary breast cancer

TopBP1 protein displays structural as well as functional similarities to BRCA1 and is involved in DNA replication, DNA damage checkpoint response and transcriptional regulation. Aberrant expression of TopBP1 may lead to genomic instability and can have pathological consequences. In this study we aim...

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Detalles Bibliográficos
Autores principales: Forma, Ewa, Krzeslak, Anna, Bernaciak, Magdalena, Romanowicz-Makowska, Hanna, Brys, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358587/
https://www.ncbi.nlm.nih.gov/pubmed/22544570
http://dx.doi.org/10.1007/s11033-012-1622-z