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Inferring serum proteolytic activity from LC-MS/MS data

BACKGROUND: In this paper we deal with modeling serum proteolysis process from tandem mass spectrometry data. The parameters of peptide degradation process inferred from LC-MS/MS data correspond directly to the activity of specific enzymes present in the serum samples of patients and healthy donors....

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Detalles Bibliográficos
Autores principales: Dittwald, Piotr, Ostrowski, Jerzy, Karczmarski, Jakub, Gambin, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358667/
https://www.ncbi.nlm.nih.gov/pubmed/22537011
http://dx.doi.org/10.1186/1471-2105-13-S5-S7